朱泉霏,博士,教授。
一、个人简介
2017年于武汉大学化学与分子科学学院获得博士学位(分析化学专业);2018年至2021年在武汉大学和澳门科技大学开展博士后研究;2022年至2023年在武汉大学公共卫生学院 特聘副研究员;2024年起武汉纺织大学生物工程与健康学院教授。 主要研究方向为基于化学衍生化的色谱质谱代谢物分析方法研究,主要致力于基于质谱的代谢组学分析方法研究,针对低丰度代谢物定性定量困难、代谢组学研究覆盖度低等问题,通过发展高效的化学衍生化辅助的液相色谱-质谱分析技术,构建基于化学标记的代谢物数据库,建立高灵敏的靶向代谢组、精细亚代谢组和非靶向代谢组分析研究平台,深度筛查和定量分析生物样品中代谢组,发现和鉴定功能性代谢物。同时,致力于利用所开发的方法,针对公共卫生/环境健康的科学问题开展合作研究。近年来在Analytical Chemistry, Trends in Analytical Chemistry等期刊上发表SCI论文50余篇,其中以第一作者或共同通讯作者身份发表SCI论文23篇。作为负责人主持国家自然科学基金青年项目1项,中国博士后科研基金1项和“澳门青年学者计划”资助1项,参与国家自然科学基金委重点项目、国际(地区)合作与交流项目以及国家科技部“973”课题等多项科研项目,入选武汉市人才计划(武汉英才优秀青年)。现为《色谱》青年编委、J. Anal. Test青年编委,湖北省生物信息学会—微生物信息学专委会委员。
二、研究领域
1. 基于衍生化技术的色谱-质谱分析方法及其应用研究;
2. 代谢组学;
三、部分代表性论文
1. Na An, Yu Wang, Dong-Xiao He, Peng-Cheng Mei, Quan-Fei Zhu*, Yu-Qi Feng*, A dataset of branched fatty acid esters of hydroxy fatty acids diversity in foods, Scientific Data, 2023, 10: 790.
2. Jun-Di Hao, Yao-Yu Chen, Yan-Zhen Wang, Na An, Pei-Rong Bai, Quan-Fei Zhu*, Yu-Qi Feng*, Novel Peak Shift Correction Method Based on the Retention Index for Peak Alignment in Untargeted Metabolomics, Analytical Chemistry, 2023, 95, 13330-13337.
3. Yan-Zhen Wang, Yao-Yu Chen, Xin-Ze Wu, Pei-Rong Bai, Na An, Xia-Lei Liu, Quan-Fei Zhu*, Yu-Qi Feng*, Uncovering the Carboxylated Metabolome in Gut Microbiota-Host Co-metabolism: A Chemical Derivatization-Molecular Networking Approach. Analytical Chemistry, 2023, 95, 11550-11557.
4. Yu-Ning Hu, Jin-Tao Zhan, Pei-Rong Bai, Na An, Jun-Jie Tan, Yan-Zhen Wang, Quan-Fei Zhu*, Yu-Qi Feng*, In-depth profiling of di(2-ethylhexyl) phthalate metabolic footprints in rats using click chemistry-mass spectrometry probes. Journal of Hazardous Materials, 2023, 452, 131190.
5. Quan-Fei Zhu, Yan-Zhen Wang, Na An, Jun-Di Hao, Peng-Cheng Mei, Ya-Li Bai, Yu-Ning Hu, Pei-Rong Bai, Yu-Qi Feng*, Alternating Dual-Collision Energy Scanning Mass Spectrometry Approach: Discovery of Novel Microbial Bile-Acid Conjugates. Analytical Chemistry, 2022, 94, 2655-2664.
6. Na An, Quan-Fei Zhu*, Yan-Zhen Wang, Cai- Feng Xiong, Yu-Ning Hu, Yu-Qi Feng*, Integration of chemical derivatization and in-source fragmentation mass spectrometry for high-coverage profiling of submetabolomes. Analytical Chemistry, 2021, 93, 11321-11328.
7. Quan-Fei Zhu, Na An, Yu-Qi Feng*, In-Depth Annotation Strategy of Saturated Hydroxy Fatty Acids Based on Their Chromatographic Retention Behaviors and MS Fragmentation Patterns. Analytical Chemistry, 2020, 92, 14528-14535.
8. Quan-Fei Zhu, Tian-Yi Zhang, Lin-Lin Qin, Xin-Ming Li, Shu-Jian Zheng, and Yu-Qi Feng*, Method to Calculate the Retention Index in Hydrophilic Interaction Liquid Chromatography Using Normal Fatty Acid Derivatives as Calibrants, Analytical Chemistry, 2019, 91: 6057-6063.
9. Tian-Yi Zhang, Sha Li, Quan-Fei Zhu*, Qing Wang, Dilshad Hussain ,Yu-Qi Feng*, Derivatization for liquid chromatography-electrospray ionization-mass spectrometry analysis of small-molecular weight compounds, TrAC-Trends in Analytical Chemistry, 2019, 119, 115608.
10. Quan-Fei Zhu, Jing-Wen Yan, Tian-Yi Zhang, Hua-Ming Xiao, and Yu-Qi Feng*, Comprehensive screening and identification of fatty acid esters of hydroxy fatty acids in plant tissues by chemical isotope labeling-assisted liquid chromatography-mass spectrometry, Analytical Chemistry, 2018, 90: 10056-10063.