导师寄语
张若筠，博士，讲师。
一、个人简介
武汉纺织大学省部共建国家重点实验室徐卫林院士团队骨干成员，武汉英才“优秀青年人才”。华中科技大学生物医学工程专业硕博连读（师从赵元弟教授，2016-2022）。参与国家自然科学基金面上项目3项、国家重点研发计划1项。在Nat. Commun.、Adv. Funct. Mater.、Chem. Eng. J.、ACS Appl. Mater. Inter.和Biomaterials等杂志发表学术论文14篇，其中第一作者7篇。获得授权发明专利2项。任SCI期刊Frontiers in Bioengineering and Biotechnology(IF= 6.06)客座编委。
二、研究领域
1.基于多功能纳米纤维的一体化诊疗平台在原位结直肠癌中的应用。
2.原位生长脱细胞生物补片用于疝气修复。
3.功能化外泌体构建生物医用材料用于骨修复。
三、代表性论文
1.Ruo-Yun Zhang, et al. Biomimetic-materials Degradation for synergistic enhanced photothermal-gas Starving therapy through regulating endogenous energy-metabolism fluorescence imaging under deep-hypothermia.Nature Communications2022, 13(1), 1-18 (IF=17.69, TOP期刊，第一作者）
2.Ruo-Yun Zhang, et al. Biomimetic O2self-generated hybrid membrane nanoplatform for blocking the polarization towards immunosuppressive M2 macrophage phenotype and enhancing sonodynamics therapy in orthotopic colorectal cancer.Chemical Engineering Journal2022, 450, 138337. (IF= 16.74, TOP期刊，第一作者)
3.Ruo-Yun Zhang, et al. Bismuth particles imbedded degradable nanohydrogel prepared by one-step method for tumor dual-mode imaging and chemo-photothermal combined therapy.Chemical Engineering Journal2019, 375: 122000. (IF= 16.74, TOP期刊，第一作者)
4.Ruo-Yun Zhang, et al. One-for-all nanoplatform for synergistic mild cascade-potentiated ultrasound therapy induced with targeting imaging-guided photothermal therapy.ACS Applied Materials & Interfaces2020, 12(36): 40052-40066. (IF= 10.38, TOP期刊，第一作者)
5.Ruo-Yun Zhang, et al. Multifunctional nanocarrier with self-catalytic production of nitric oxide for fluorescence imaging-guided photothermal and gas combined therapy of tumor.Journal of Colloid and Interface Science2022, 621, 77-90. (IF= 9.96, TOP期刊，第一作者)
6.Ruo-Yun Zhang, et al. A pH/ultrasonic dual-response step-targeting enterosoluble granule for combined sonodynamic-chemotherapy guided via gastrointestinal tract imaging in orthotopic colorectal cancer.Nanoscale2021, 13(7): 4278-4294. (IF= 8.31, TOP期刊，第一作者)
7.Ruo-Yun Zhang, et al. Folic acid modified Pluronic F127 coating Ag2S quantum dot for photoacoustic imaging of tumor cell-targeting.Nanotechnology2018, 29: 055101. (IF= 3.95, TOP期刊，第一作者)
8.Yang Xuan, Ruo-Yun Zhang, et al. Ultrafast synthesis of gold nanosphere cluster coated by graphene quantum dot for active targeting PA/CT imaging and near-infrared laser/pH-triggered chemo-photothermal synergistic tumor therapy,Chemical Engineering Journal2019, 369: 87-99. (IF= 16.74, TOP期刊)
9.Yang Xuan, Ruo-Yun Zhang, et al. Targeting N-doped graphene quantum dot with high photothermal conversion efficiency for dual-mode imaging and therapyin vitro,Nanotechnology2018, 29, 355101. (IF= 3.95, TOP期刊)
10.Xiao-Quan Yang, Ruo-Yun Zhang, et al. High-security multifunctional nano-bismuth-sphere-cluster prepared from oral gastric drug for CT/PA dual-mode imaging and chemo-photothermal combined therapyin vivo,Advanced Functional Materials,2019, 29, 1900017. (IF= 19.92, TOP期刊)
11.Xiao-Shuai Zhang, Ruo-Yun Zhang, et al. A multifunctional targeting probe with dual-mode imaging and photothermal therapy usedin vivo,Journal of Nanobiotechnology2018, 16, 42. (IF= 9.42, TOP期刊)
12.Kai Cheng, Ruo-Yun Zhang, et al. Hitherto-Unexplored photodynamic therapy of Ag2S and enhanced regulation based on polydopaminein vitroandvivo,Chemistry-A European Journal2019, 25, 7553-7560. (IF= 5.02, TOP期刊)
13.An Jie, Zhang Ruo-Yun, et al. A pH/ultrasound dual-response biomimetic nanoplatform for nitric oxide gas-sonodynamic combined therapy and repeated ultrasound for relieving hypoxia.Biomaterials2020, 230, 119636. (IF= 15.34, TOP期刊)
14.Cheng Kai, Zhang Ruo-Yun, et al. High-security nanocluster for switching photodynamic combining photothermal and acid-induced drug compliance therapy guided by multimodal active-targeting imaging.Advanced Functional Materials2018, 28(36): 1803118. (IF= 19.92, TOP期刊)
